Fiber laser systems for multiphoton microscopy

Fiber lasers have greatly evolved over the last years, becoming a significant force in manufacturing and high technology.

Fiber laser technology is still expanding its limits in the list of various applications. High-power lasers change the machining industry and our economy fundamentally, while low-power highly accurate fiber lasers are applied in medicine, biotech and physical sciences. Fiber lasers’ popularity increase is a result of their end-use benefits, such as reliability, usability, operation stability, etc.Fiber laser systems for multiphoton microscopy

What is multiphoton microscopy?

Multiphoton microscopy is a laser scanning microscopy method. In this technique there are as little as two or three photons. They are combined to generate high resolution 3D images of microscopic samples.

Laser microscopy has turned out to become an instrument in material development and studies. It is mostly applied in biological sciences and tissue engineering. Scientists use it for imaging of living biological tissues that can be conducted due to different scales whether on the molecular levels or through the whole organism.

During the experiments, multiphoton microscopy (MPM) is able to provide the most accurate measurements of the biological activities. Measurement procedures can last from several seconds to weeks, or even months that would cause some discomfort for patients. In these cases, minimal invasion plays a crucial role for them, besides, providing the most precise results.

This far-field imaging is developing rapidly and demands more complicated contemporary fiber lasers. The further progress will expand the capabilities of multiphoton microscopy in observing biological processes within deep layers of living tissues with minimal damage.

Fiber laser systems in multiphoton microscopy

As for multiphoton microscopy, fiber lasers are essential elements of this technology. Compared to usual lasers, fiber laser modules have a range of advantages.

  • Due to the absence of a separate optical medium for beam delivery, fiber lasers are more stable and easier to maintain. They provide very high levels of optical gain.
  • In comparison with traditional CO2 lasers, fiber lasers have a higher power conversion rate, they are energy efficient.
  • Thanks to the highly focused narrow laser beam, laser modules can be applied in complex designs where there is a necessity in high precision.
  • Fiber lasers don’t have any moving parts that require regular servicing.
  • Fiber laser systems can be more expensive than other lasers on the market. However, the previously mentioned benefits reduce ownership cost and make fiber lasers cost-effective. Along with the less maintenance, the other factor – less power – helps in reducing the operating costs.

Applications of fiber laser systems in multiphoton microscopy

Thanks to the modern fiber lasers’ abilities and above-mentioned advantages, fiber laser technology is developing and still is looking for its limits.

Multiphoton microscopy is applied in various medical and biological fields.

Fiber lasers for oncology

Multiphoton microscopy measurements have proven to be one of the most effective imaging instruments when there is a necessity in detection of the malignancy. This instrument is able to identify malignancy of affected areas. For example, it can help medical specialists in bladder evaluation in real time and impression of extracted bladder tissue. Along with bladder cancer, multiphoton microscopy is also applied to evaluate prostate cancer. Multiphoton microscopy uses fiber lasers, and as any medical procedure, requires preliminary analysis.

Fiber laser systems for immunology

Multiphoton microscopy is able to image cells in vivo effectively. However, there is a need for an appropriate fiber laser that plays a significant role. This technology requires an accurate fiber laser that due to its qualities is able to create contrast in scattering tissue and at the same time reduce phototoxicity and photobleaching. Thanks to multiphoton microscopy, immunology has broken new ground, for example, by intravital imaging of leukocytes at a single-cell level.

Orchestration of cell migration, interactions between cells and intracellular signaling events have become possible because of the up-to-date technology of the multiphoton microscopy. Not so long ago multiphoton microscopy was applied only in a few specialized laboratories. Nowadays, this technique that uses fiber laser systems is far more extended and has become more publicly available.

Fiber lasers for neuroscience

Multiphoton excitation with the fiber laser pulses have given an opportunity to get the high-resolution images. With the increasing role of microscopy, fiber laser technology has also developed and proved to be the most suitable.

Neuroscience is one of the most modern research areas. Specialists study a variety of the neuronal networks to find out the nature of brain pathologies and create a treatment for neurodegenerative diseases. Nowadays, scientists have received an ability to analyze brain activity during the interaction of the brain and visual organs, carrying out some operations, etc. The observation of the brain operations is necessary for understanding of its functioning and pathological conditions’ appearance.

Deep brain imaging helps with these purposes. However, there are factors that should be taken into account during the fiber laser designing, for example, providing the proper volume. The problem is the deeper the penetration, the worse image quality. As a result, fiber lasers are the most suitable for neuroscience because fiber laser systems are power scalable.

Laser modules for spermatogenesis

Multiphoton microscopy makes the visualization of different biological processes in live tissues possible. For spermatogenesis multiphoton microscopy uses fiber lasers for visualization of all tubules with and without sperm.

As a result of the latest development, this technology of sperm extraction has replaced conventional testis biopsies. Nowadays, specialists are improving new technology and solving other challenges. Due to modern technology, the tubules’ retrieval relies only on appearance. So, in the future multiphoton microscopy has every chance to help real-time visualization improvement and apply it in clinical applications.

All in all, fiber laser systems are considered to be suitable and remarkable instruments for multiphoton microscopy that leads to the expansion of the boundaries in science and medicine. Multiphoton microscopy as well as laser modules give an opportunity to develop the treatment of such diseases as epilepsy, Parkinson, etc.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber lasers in flow visualization

Since the invention of the first fiber laser module, these systems have found a range of applications in a number of scientific studies related to biology, chemistry, astronomy, etc. In the future, scientists are going to develop more contemporary fiber lasers due to the challenges of the modern world. Nowadays, fiber laser systems participate in a number of various field experiments from triggering lightning in thunderclouds to genomics.Fiber lasers in flow visualization

Advantages of the fiber laser systems

A fiber laser is a well-structured compact laser that provides high electrical and optical efficiency. Fiber lasers are reliable and capable of delivering well-controlled and accurately directed laser beams. By amplifying specific wavelengths inside optical fibers specialists are able to design a fiber laser system with excellent beam quality and high peak energy.

Lasers are not intended to be light sources as illumination devices. However, they are good at light concentrating in space or particular wavelengths. The majority of laser applications can be divided into three segments:

  • the data transmission and processing;
  • accurate delivery of energy;
  • alignment, measurement, and imaging.

Fiber lasers have many significant advantages in comparison with the other laser types. Except for the previously mentioned high-quality laser beam and many other features, laser modules are powerful due to their high brightness. Fiber lasers don’t require any additional maintenance because optical fibers are set up without any mirrors and lenses.

Flow visualization with fiber lasers

Flow visualization is a technology that is applied to make the flow patterns visible for getting qualitative or quantitative data about them. This method is to observe the behavior of particles in the air stream. Lasers help to see the direction and uniformity of the air flow.

Particle image velocimetry (PIV) is one of the technologies that refers to the flow visualization. It has received great popularity in a range of scientific and engineering spheres. PIV technology is required when there is a necessity in measurements of various fluids and gas characteristics, for example, instantaneous velocities.

A custom PIV system includes a multi-pulsed fiber laser system, at least one camera synchronized with the laser, and a computer to display the received information.

Specialists can apply CW or pulsed fiber lasers in the acquisition process of PIV data. Fiber lasers are used because they are highly powerful with short pulse durations. Fiber laser modules make small implemented tracer particles visible. With the flow of the fluid, they are moving at the same pace. Then with the help of a camera a series of photos is taken which are used for further calculations of particles’ speed or direction.

Applications of the PIV technology

Due to its capabilities, particle image velocimetry has found its applications in many fields where highly macro and microscopic scales are used.

As any other fiber laser-based application, PIV is a technology that requires highly reliable laser modules. In reality, they have to operate in harsh environments that bring some difficulties outside the lab. That’s why specialists are mostly interested in creating robust and cost-effective laser modules.

Particle image velocimetry systems are proved to be valuable instruments. They are applied in a range of industries, for example, in aerospace, agriculture, medicine, etc.

Here are some more detailed examples of applications that fiber lasers have as PIV technology components.

Automation and quality control processes for gas and liquid production. PIV technology based on the most modern methods can be applied for the simultaneous measurements of the velocity and turbulence fields including gas and oil production.

Measurements and analysis of the indoor airflow fields. It can be complicated to measure a complex turbulent flow field accurately. That’s why the PIV technique is used to meet these challenges. A number of studies have demonstrated this technology’s effectiveness and named it one of the most universal instruments for measuring. Depending on the scientists’ purposes, they can choose a range of parameters for measurements. Despite some limitations for PIV systems, the obtained data about indoor flow is essential for validating numerical simulations and analyzing.

Combustion diagnostics. PIV technique has become an advanced instrument for combustion constructions. Its optimization, including improvement of the in-cylinder flow structures, is necessary due to new emission regulations focusing on reduction of pollutant formation in engines. When we are talking about combustion diagnostics, there are some challenges. Due to the engines’ structure, it’s complicated to analyze any changes.

PIV technology in medicine. In addition to the technical measurements, PIV has been widely applied in evaluation of the medical devices’ performance, for example, of the blood pumps, artificial heart valves, etc. It can also make predictions of the blood damage potential that different medical devices have. This technology mostly depends on the quantity of the images, their resolution and quality.

Nowadays, PIV technology has proved to be effective, and specialists are still looking for new ways of its applications for various systems. Fiber lasers, in turn, have played a great role in its development thanks to their advantages compared to the usual production equipment.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber laser modules in various fields of medicine

Since the creation of the first laser modules, specialists have conducted intense research on the effects of laser radiation on biological tissues. Fiber lasers have greatly helped in developing a number of treating methods of various diseases.Laser modules in medicine

The main advantages of fiber laser modules in medicine

In accordance with radiation power, laser modules can be used in different ways including heating, cutting, or coagulation of biological tissue. Here are the advantages of medical instruments with fiber lasers when they are compared to the traditional medical equipment:

  • fiber lasers can provide non-invasive or minimally invasive cut;
  • high temperature helps in sterilization of the wounds, reducing the risk of infection;
  • there is minimal swelling of wounds;
  • reduction of the postoperative consequences;
  • postoperative period is reduced.

Nowadays, fiber lasers have found their applications in otorhinolaryngology, treatment of vascular diseases, cardiac surgery, orthopedics, traumatology, neurosurgery, gynecology, proctology, dentistry and other fields.

Fiber lasers’ radiation levels and their applications

Due to the fiber laser wavelength, different effects of radiation on biological tissues are possible. It depends on the optical properties of the fiber laser radiation, namely, the absorption coefficient, scattering coefficient, and also on moisture saturation. Absorption of radiation in biological tissues determines the depth of penetration. Water and hemoglobin are the main substances that absorb radiation in biological tissues.

Here are the most common laser modules’ radiation rates that are applied in the medical industry:

  • 0.94-0.98 µm radiation is an optimal mix of cutting and coagulation for surgery;
  • 1.06 μm radiation is used for controlled volumetric tissue heating;
  • 1.4–1.8 μm wavelength differs from the previous ranges. Water heating 100 °C and its further evaporation plays the crucial role;
  • The next wavelength range that is applied in medicine is 1.8–2.1 μm. The laser modules with such radiation, similar to CO2 lasers, provide good cutting properties, small zone of thermal damage and good coagulation;
  • Nowadays, lasers with wavelength >2 μm have already found a wide range of applications. However, scientists are confident that more ways to use it can be found. The wavelengths between 2.05 µm and 2.3 µm are operating in the atmospheric transmission window. Most of all these laser modules are applied where safety of vision is strategic.
  • Thulium-doped fiber lasers can provide a wavelength range of 1900 – 2000 nm that meets the absorption peak in biological tissues:
    • Fiber lasers with a power of up to 10 W are applied in cosmetology and dentistry;
    • Lasers with a power of 40 W are used with great success in gynecology, proctology and vascular pathology treatment;
    • Fiber lasers with a power of 50-120 W are applied in urology for transurethral vaporization of the prostate.

Features of fiber lasers’ use in medicine

Nowadays, fiber lasers are applied in a number of technical and scientific fields due to their qualities. Laser modules are compact, irresistible to vibrations and electromagnetic radiation and can be equipped with a variety of commercially available components.

Due to the variety of pathologies and great number of diseases, there should be an individual approach to every fiber laser system. Specialists provide the accurate set of laser operating modes for every specific medical field. Fiber lasers have made great progress in reduction of injuries during operations and making the recovery period shorter.

It should also be mentioned that laser modules are significant instruments in modern surgery as an endoscopic technology. Fiber lasers are fully compatible with surgical endoscopes, at the same time providing minimally invasive surgery.

Currently, in the rapidly changing world of fiber laser technology, laser modules are widely produced in biology and medicine. In the future, scientists are going to study the effect of laser radiation on artificial and natural biological tissues further and optimize the parameters of fiber lasers.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Laser modules in optical pumping and optical trapping

Laser modules are applied in various industrial spheres due to the broad spectrum of produced wavelengths. High-power fiber laser systems are commonly used for welding, marking, cutting, etc. Low-power but more precise fiber lasers fit for applications where there is a need for high accuracy, for example, for science and medicine.

This article is dedicated to the two applications of low-power fiber laser modules such as laser pumping and optical trapping.Laser modules in optical pumping and optical trapping

Most common advantages of the laser modules

Laser diodes are applied in optical pumping of fiber lasers and DPSS. They are proved to be extremely effective, robust and compact in the laser industry. What is more important, laser modules provide high peak energy and stable laser beam quality. Let’s see all these advantages in detail:

  • The idea of photons’ limiting in rare earth-doped fiber gives fiber lasers priority over the other laser types. That is stability. Since a fiber laser generates the beam within the core, there is no need for complex or sensitive optical equipment. At the same time in a usual laser there is an optical fiber for laser beam regulation. Otherwise, optical fiber is applied for the mirror reflection. Both these operation principles constantly require highly accurate adjustment by the specialist every time they fail. Unlike conventional lasers, fiber lasers don’t have such a high level of sensitivity to the movements and shocks, keeping the operation stability the same.
  • To provide the straight and high-quality laser beam, there is a limitation by the doped fiber core. As a result, the focusing made by the laser beam is more accurate and effective.
  • Energy efficiency is the other strength that fiber lasers have. They can transfer almost all the input they get into the beam. Therefore, the limitation of energy amounts reduces the conversion to thermal energy. That makes fiber better thermally protected and immune to degradation.
  • Nowadays, the majority of laser sources have water-cooled operating systems. In contrast to them, fiber lasers use air cooling technology to take the heat out of the laser. This fact lets specialists solve the portability and power consumption issues. The specialists have developed the most effective cooling systems based on the heat dissipation calculations for different parts and a number of comprehensive studies of thermal loading. Due to the modern chilling systems, thermal dissipation of the fiber lasers with the air cooling technology is proved to be a highly effective method in mitigation of the thermal effects.
  • Fiber laser systems with 1 – 100 W output power ranges offer a wide choice of different wavelengths.

Fiber laser systems in optical pumping

Optical pumping of a certain laser medium is its illumination by an external light source in order to transfer it to an excited electronic state, the entire environment or its components. Fiber lasers, as all fiber laser systems, need an excitation source to pump energy into the system.

Nowadays, the most common forms of optical pumping include semiconductor lasers (laser diodes), solid-state, or fiber lasers. Solid-state and fiber lasers are pumped with laser diodes.

Laser pumping can be made in two methods: continuous or pulsed modes. The key distinction between these types is the delivery method of laser pumping source which is connected to fiber core and then fused into a double clad fiber. This double clad fiber is alloyed with certain material for the particular laser module. According to the applied material, the absorption band can be wide or narrow. It means that there can be applied conventional laser diodes, or wavelength stabilized diodes in some cases.

Fiber laser modules in optical trapping

Optical trapping is a scientific instrument applying a focused laser beam to hold and manipulate microscopic objects. Mostly this technology is effectively used in biomedical studies.

Thanks to the ability to work with nanoparticles, optical trapping can study the single molecules. That’s why progress in optical trapping has greatly helped in research of DNA properties and associated proteins.

Most of the optical trap systems employ laser modules with the 1 μm wavelength. For them, these lasers are necessary because their chances of biological material’s damage are lower. Such wavelength is optimal for aqueous biological specimens with a low absorption coefficient.

With both these instrument types scientists apply laser modules in modern micro- and nanotechnology. The efficiency of optical trapping and optical pumping has brought new opportunities to science.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber laser systems for scientific research

Fiber laser technology has proved to be an effective instrument in a number of various fields and applications. If it comes to the field of science, fiber laser systems are applied in medical sciences, biology, micromachining, etc. Fiber laser is in many ways the best solution for professional engineers and researchers for their projects’ development.Fiber laser systems for science

The most general characteristics of the fiber laser systems

The top quality of the laser beam, great performance and power efficiency have helped fiber lasers to find a place in many areas of scientific and biomedical studies. Fiber lasers imply an ultra-narrow linewidth and reliable working operation thanks to the short cavity length and phase-shifted design.

The single-frequency fiber lasers are perfectly fit for various applications due to the various ranges of frequency or wavelength. Such applications include, for instance, optical trapping and atom cooling. The other parameters of laser modules, like compact size and low noise, make it possible to use it in interferometric sensing.

Laser engineers and scientists are constantly looking for new opportunities for the fiber lasers and developing more sophisticated technologies.

Types of fiber lasers due to their parameters

Fiber laser systems can be classified due to many categories, but there are parameters that play a crucial role in operations. These features are listed below.

  • Laser power. High-power fiber lasers provide more energy and operate faster in comparison with low-power lasers. Laser power is measured in watts.
  • Mode. This parameter relates to the core’s size in the optical fiber. There are single-mode and multimode fiber lasers. The single-mode lasers have a smaller diameter of the core and transit laser light successfully and at the same time providing a better laser beam quality. Multimode lasers have larger diameter in comparison with the single-mode ones.
  • Laser source. Lasers can also be varied considering the applied material of the laser source. There are thulium-doped fiber lasers, erbium-doped fiber lasers, ytterbium-doped fiber lasers, etc. Each of them has different wavelengths and fields of application.
  • Operating mode. The difference of fiber lasers depending on the operating mode is connected to the way the laser beam is released. There are usually lasers with continuous-wave or the pulsed mode. The pulsed lasers have the short pulses that are released at an established repetition rate. While in the continuous-wave operation mode, a continuous laser beam is released. Simply put, its amount of energy is at the same level all the time.

Fiber lasers for science in short

Fiber lasers are considered to be a unique technique suitable for many applications that can be combined into one sphere called the science.

Talking about science, laser modules perfectly fit for biophotonics, multiphoton microscopy, neuroscience, etc. From the date of creation, a fiber laser has been applied as an instrument for research in astronomy, physics, biology, chemistry, etc.

Ultra precise fiber laser technology covers a variety of medical and scientific disciplines, where fiber lasers are already used, or their strong impact is possible, for example:

  • High energy physics;
  • Attosecond science;
  • Ultrafast X-ray science;
  • High harmonic generation;
  • Femtosecond chemistry, etc.

The ultrashort pulse fiber lasers allow conducting scientific and medical research in different fields. The fiber laser systems with the mid-infrared wavelength range provide the analysis of biochemical content of tissues.
Here are some other spheres where fiber lasers are applied.

Fiber lasers for SFG spectroscopy

One of the applications of the fiber laser systems is SFG spectroscopy. Spectroscopy provides detailed data on the molecular level about the structure and molecular groups by studying the atoms’ vibrations.

This technology outperforms the traditional methods by the means of good qualities like vibrational specificity and surface sensitivity. In this approach laser beam quality is important because it generates the SFG signal. Due to spectrometers’ abilities to effectively provide precise measurements and vibrational spectroscopy studies, they are often applied for chemical and biochemical laboratories, as well as for the studies in physics, material science, etc.

New approach for fiber lasers in plasma physics

In plasma physics scientists have recently suggested a new way of working with high-power lasers for the accelerators. They have got an idea of combining the lately developed laser modules with laser-plasma accelerators.

The fiber lasers are fast and compact. That helps in the creation of compact and well-managed accelerators that can be applied in various related spheres, like high-energy physics or biomedical treatment. The researchers are planning to use an intense laser beam fired through a gas to generate a plasma wave.

Ultrafast fiber lasers for optogenetics

Fiber lasers have also found another application in the specific sphere of neuroscience called optogenetics. Optogenetics is a field of biophotonics. It is a recent approach that has provided new opportunities for brain study. Due to this technology, researchers can study the neurological activity in particular cells of the brain. The research and studies in this field will assist the developments of treatments for neurological and psychiatric disorders.

The concept is to use fiber lasers for the exploration of the brain’s neural network. Scientists study it with the help of the light that activates or inhibits signaling of neurons in the brain. Fiber lasers provide the necessary laser beam quality and accurate modulation. Moreover, laser modules are compact and cost-effective which makes them easy to use.

Fiber laser systems possess some benefits over the other lasers that’s why they have more and more applications in different scientific areas. During all these years fiber lasers have achieved fast progress and led to modern inventions. Their advancement demonstrates excellent physical and other characteristics.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber lasers and their applications in medicine

Fiber lasers have received much attention because of their qualities, benefits in use and a number of applications in various spheres. A range of the different wavelengths allows specialists to use fiber laser systems in factory environments for welding, cutting, texturing, etc. At the same time, the ultraprecise fiber lasers are applied in spheres where accuracy is a crucial feature – for example, in medicine, micromachining or scientific research.Fiber lasers and their applications in medicine

History of the fiber lasers’ development

The history of the fiber lasers’ evolution began with the invention of the first laser in 1961. First lasers didn’t achieve great of popularity from the very beginning, as they were complex and quite expensive. Fiber lasers got serious commercial applications only in the 1990s. The main cause is the gradual development of the fiber laser technology.

Today, fiber laser technology is still improving, creating more powerful and efficient fiber lasers. Specialists are working on the lasers’ accuracy, lasers’ environmental impact, etc. More improvements were made when the outputs of multiple fiber lasers were combined. This modification has led to the improvement of the power and range of the laser beam.

Medical applications of ultrafast fiber lasers

When it comes to fiber lasers’ applications, ultrafast fiber laser systems are applied in various spheres. However, there are fields where fiber lasers are irreplaceable, for instance, in medicine.

Fiber laser technology has made a great contribution to the growth of medicine. Fiber lasers are applied in fields ranging from therapy and ending with surgery. Thanks to the tremendous demand for healthcare, fiber laser technology has grown into a mature industry by making new innovations. Fiber lasers have rapidly adapted to the medical procedures’ evolution, considering their high-power densities in sterile noncontact processes and providing cauterization.

Fiber lasers in photodynamic therapy

PDT or Photodynamic Therapy is a treatment where the fiber laser light is used to destroy abnormal cells. From the very beginning, this technology was specially developed for the cancerous and precancerous cells in oncology. Moreover, it was suitable just for the particular cancer types.

The further development of PDT demonstrated that it can also be effective for general oncology and other kinds of cancer. This method is more convenient for the patients because it represents a noninvasive or minimal invasive alternative technique and provides less time for the recovery.

Fiber lasers in dentistry

The other medical field where fiber lasers have been applied over recent decades is dentistry. Fiber laser systems have proved to provide a fast and easy way of treatment. Fiber lasers have offered a significant reduction of the pain during or after the treatment for the patients. Moreover, the time required for the procedure itself and for the recovery period has got shorter.

Fiber lasers’ requirements in this sphere can be diverse starting from the essential laser characteristics like the wavelength and ending with physical qualities like size.

Fiber lasers for optical coherence tomography

From the very beginning, optical coherence tomography was developed particularly for ophthalmology. Meanwhile, today optical coherence tomography has found many applications in medicine.

The laser beam light is applied to take the cross-section images for diagnostics in clinics. The good resolution of the image helps in finding tiny infections at a few millimeters depth at the early stage. It is applied for diagnosis and treatment of diseases, monitoring of the therapeutic efficacy and different processes.

Fiber lasers for aesthetic applications

Laser modules have also become necessary instruments in some aesthetic, cosmetic or dermatology procedures. Previously, the CO2 lasers were produced for these purposes. However, due to fiber lasers’ recent development and advances, fiber lasers demonstrated their effectiveness as well.

The fiber laser systems are increasingly applied for performing radiation treatment on a patient. The fiber lasers are distinguished by their wavelengths, quantity of laser beams, design, etc. The wavelength can define a desired efficiency and depth of penetration for the treatment of the certain body part. The plurality of the fiber lasers may be placed next to one another to provide radiation along a line or located to achieve only the selected spaced areas of damage.

The most common fiber lasers applications in aesthetic procedures are skin resurfacing and tattoo removal. If we are talking about more complicated procedures, fiber lasers are applied for treatment of vascular lesions, skin micro-preparation, psoriasis, etc.

Considering all the progress that fiber lasers have already achieved over the past few years, scientists are still focusing on the development of more powerful and precise fiber laser systems. Fiber laser technology is applied by many specialists from different spheres for medical procedures and scientific research. Thanks to the fiber lasers advantages, they have become an essential tool for a lot of industries and spheres.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber laser systems kill bacteria in the human body

Recently, scientists have developed new fiber laser systems that can kill bacterial superbugs and spores. The bacteria that can threaten human life get used to any medicine, including antibiotics. This fact made developers look for other ways of treatment. And for some applications, the alternative can be a special ultrashort-pulse fiber laser.

Fiber laser systems kill bacteria

Fiber laser modules’ effects

Researchers from the United States have discovered that fiber lasers that emit ultrashort pulses of light are able to eliminate bacteria resistant to drugs. Scientists explored the ultrashort-pulse lasers’ germicidal characteristics and found out that fiber laser modules are able to inactivate such bacteria and viruses without destroying human cells. They used the most common viruses and bacteria to look at the effect of the lasers on them. Among them are those which cause infections of the skin, or different organs, urinary tract infections, and wound infections. Researchers also took various types of spores that cause food spoilage and food poisoning. Some of them withstand cooking and boiling.

All bacteria and viruses include protein structures. The ultrashort-pulse fiber laser makes these structures vibrate until their molecular bonds break. As a result, there are incorrect linkages between protein structures that lead to a halt of normal protein function.

In fact, to achieve the desired results the scientists have to provide accurate laser power. To get viruses and bacteria inactivated there should be different laser powers. But if these power limits are higher, the laser starts killing human cells. So there is some power interval to destroy pathogens but reserving the human cells healthy.

Future of this fiber laser technology

Firstly, the developers see the future for this ultrashort-pulse fiber laser technology in inactivating pathogens and preserving human proteins and cells at the same time. With the help of this technology, it would be possible to disinfect a surgical wound with a laser beam, or even to treat bloodstream infections. Moreover, this fiber laser technology can be applied as a replacement for chemicals like bleach or radiation because they can be damaging to people. Ultrashort-pulse fiber lasers can become a new way to provide safety to various biological or blood products.

According to the results, fiber lasers have killed about 99.9% of the target bacteria and reduced their quantity by 1,000 times. Moreover, such fiber lasers don’t harm human cells that can be applied in wound sterilization or disinfection.

Optromix Inc., headquartered in Newton, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber lasers technology applications for cancer operations

Fiber laser technology has already become one of the most powerful instruments in medicine, and cancer treatment is not an exception. Laser therapy represents an intensely focused laser beam for cancer cells, destroying or shrinking. It can be applied to remove tumors with tissue-preserving. Laser therapy aims to treat a certain part of the body and prevent further disease development.
In comparison with healthy cells, tumor cells absorb light of various wavelengths. That’s why the rightly chosen fiber laser wavelength can help in tumor cells’ destruction. 

How fiber laser therapy is applied

Fiber laser treatment is mostly applied in surgery, where doctors have to perform difficult operations and where there are high risks for patients. Thus, fiber laser systems can help in reducing pain, swelling, and bleeding. Specialists have an opportunity to seal lymphatic vessels, nerve endings, and blood vessels to avoid all complications during or after operations.
Fiber lasers can be used on absolutely different cancer stages. They are able to limit the spread of cancer cells or treat precancerous cells on the different surfaces of the internal organs. They can also ease some symptoms of advanced cancer. For instance, fiber laser modules can destroy parts of a tumor.
Nowadays, fiber laser therapy is implemented using a flexible endoscopic fiber catheter. It represents a narrow tube for monitoring tissues inside the body. The endoscopic fiber catheter inserted into the body transmits the light to the therapy site. Specialists can destroy or cut a tumor with the use of a laser beam.

Advantages and disadvantages of the fiber laser therapy

In comparison with the usual surgery, fiber lasers have several advantages and disadvantages. 
Fiber lasers more accurately seal the cut tissues from bleeding. Moreover, they can bring less damage to tissues that leads to other benefits. For example, patients have less pain, scarring, etc. It takes less time for the operations. After the operation, patients have a faster recovery. Furthermore, the operations with the help of the fiber lasers can be conducted in a doctor’s office, not in a hospital.
However, despite all the benefits that fiber laser systems have, there are still drawbacks that we need to keep in mind. Firstly, fiber laser therapy is more expensive in comparison with conventional surgery tools. But in fact, specialized fiber laser equipment is considered to be cost-effective and often wins because it is more convenient both for patients and for specialists. 
Secondly, laser therapy requires special training to work on such equipment. There is a problem finding skilled personnel for the hospitals and medical centers. 
Thirdly, it’s rather sad to say, but the effects of the operation may not last long. This means that specialists need to repeat it to get the full recovery. 
In conclusion, it should be said that despite all the disadvantages, fiber laser systems provide more benefits, which are obviously very important for patients and doctors. At the very least, they make operations safer and more convenient for everyone. 
Optromix Inc., headquartered in Cambridge, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

The diversity of fiber laser applications in medicine

Many articles about lasers that can be found on the Web are about high-power fiber lasers, which are showy, associated with science fiction, and are commonly used in industry. However, fiber lasers are popular with buyers in other industries. Although they are not as powerful, they have found their way into many areas, such as medicine.

Fiber laser technology benefits 

Fiber laser technology is considered to have a great impact in medicine by creating new applications. Thanks to their unique features and versatility, they can be applied both in diagnostic imaging and surgery. Despite their lower power rates, they are able to provide the highest levels of accuracy. In fact, it allows providing safe and contactless processes for the patients. Moreover, medical personnel find them one of the easiest to use equipment, thanks to fiber lasers‘ compactness. 
There are various fiber lasers that are able to operate in their unique manner and can be applied for many treatments. Laser beam light can be delivered whether continuously or intermittently. By adjusting the wavelength, specialists can determine the effect on the skin and achieve the desired results. All of these factors can be regulated during fiber laser manufacturing depending on the effect a laser needs to provide. 

Most common applications of the fiber lasers

Here are several spheres where fiber lasers can be used:

Medical diagnostics and imaging

Nowadays, specialists have learned to detect a number of various diseases by registration of any changes in molecular composition. For example, endoscopic fiber catheters can provide an imaging diagnostic of an artery during bypass surgery performance. 

Optical Coherence Tomography

Fiber lasers with a large spectrum are usually applied in OCT to provide cross-section images for diagnostics.  

Aesthetic Applications

Medical procedures such as tattoo removal or skin resurfacing usually require CO2 lasers. However, recent research has shown that conventional fiber lasers can also be efficient and used effectively.

Laser Surgery 

Laser surgery uses light beams for surgical procedures. When light from the laser beam hits the skin, there are several ways the skin responds. The skin can reflect the light away, scatter it, or let it through layers of the skin. There are certain parts of the skin that absorb the light causing different tissue changes.
Mostly, fiber lasers are applied to destroy or shrink tumors, to seal small blood vessels in preventing blood loss, etc.
All in all, we should say that fiber laser systems still remain one of the most effective medical instruments proven to gain the trust of both medical specialists and patients.
Optromix Inc., headquartered in Cambridge, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com

Fiber lasers for aesthetic treatments

It is not a secret that fiber lasers have rapidly become one of the most popular instruments, thanks to all the benefits they offer. They have influenced many spheres such as industry, science, and so on. That fact has ensured their fast development. And medicine is no exception.

Fiber Lasers’ medicine applications

Laser modules have found many implementations in medicine, starting from diagnosis and ending with micro-cutting applications in surgery. Thanks to the development of fiber laser technology, medical procedures became easier both for the personnel and patients in urology, spinal surgery, brain tissue treatment, ophthalmology, etc. 
When the first fiber laser was designed, its commercial availability made it possible to use it in many spheres. They were in high demand because it was clear that the healthcare system needed some improvements. That’s why fiber laser technology had achieved tremendous growth in advancement and innovations.

Moreover, fiber lasers have got other applications like aesthetic treatments. They are widely applied in skin resurfacing or tattoo removal, where high-energy lasers are required. Previously, CO2 lasers were mostly used for these purposes. However, recent studies have demonstrated fiber lasers‘ effectiveness as well. The usage of fiber lasers in plastic surgery and cosmetic treatment provided lower risk and excellent results. Patients choose them because this method is non-invasive and doesn’t require post-treatment recovery time.
All in all, fiber lasers are considered to be one-of-a-kind light sources because of their numerous advantages in performance. 

Fiber Lasers advantages

Fiber Lasers‘ universality helps them to be very effective in a number of spheres simultaneously. Here are their main advantages:

  • high level of precision;
  • contactless process;
  • compact size;
  • high efficiency; 
  • high laser beam quality;
  • cost-effectiveness, etc. 

In conclusion, we can say that thanks to the numerous researches, fiber lasers have got a wide range of diversification. Nowadays, they can differ due to their operating modes, energy levels, wavelengths, etc. So scientists see them as a future instrument in further medicine modernization. 
Optromix Inc., headquartered in Cambridge, MA, USA, is a manufacturer of laser technologies, optical fiber sensors, and optical monitoring systems. We develop and manufacture a broad variety of Fiber lasers, СО2 lasers, Ti: Sapphire lasers, Dye lasers, and Excimer Lasers. We offer simple Erbium laser and Ytterbium laser products, as well as sophisticated laser systems with unique characteristics, based on the client’s inquiry.
We manufacture laser modules using our technologies based on the advanced research work and patents of the international R&D team. Laser processes are high-quality, high-precision, easily automated manufacturing solutions that provide repeatability and flexibility.
If you are interested in Optromix fiber laser systems or Optromix CO2 lasers, please contact us at info@optromix.com